Flupirtine maleate, Neuronal potassium channel opener (ab142432)
Key features and details
- Neuronal potassium channel opener
- CAS Number: 75507-68-5
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Flupirtine maleate, Neuronal potassium channel opener -
Description
Neuronal potassium channel opener -
Biological description
Neuronal potassium channel opener. Activates Kv7.2 channels and potently activates the inwardly rectifying potassium current (KIR; EC50 = 600 nM). Centrally acting, non-opiate analgesic. Neuroprotective and antiapoptotic agent. Also has muscle relaxant properties. Active in vivo.
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Purity
> 99% -
CAS Number
75507-68-5 -
Chemical structure
Properties
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Chemical name
Ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate maleate -
Molecular weight
420.40 -
Molecular formula
C15H17FN4O2.C4H4O4 -
PubChem identifier
6435335 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=CC(=O)O)C(=O)O -
Source
Synthetic
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Research areas
