FITC Anti-DR4 antibody [DR-4-02] (ab59047)
Key features and details
- FITC Mouse monoclonal [DR-4-02] to DR4
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-DR4 antibody [DR-4-02]
See all DR4 primary antibodies -
Description
FITC Mouse monoclonal [DR-4-02] to DR4 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
The antibody recognizes TRAIL R1 (DR4), a human death receptor 4 (468 amino acids) expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour derived cell lines. -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein (Human) containing the extracellular part of DR4 and the constant part of the heavy chain of human IgG1.
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General notes
Do not use after expiration date stamped on vial label. Short term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.Soluble antibody blocks DR4 receptor against TRAIL induced apoptosis. Plastic immobilized antibody induces apoptosis in sensitive cells.
The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituent: 0.2% BSA
0.2% high grade protease free BSA -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
The antibody was >95% pure prior to conjugation as determined from SDS-PAGE (by protein A affinity chromatography). -
Primary antibody notes
Soluble antibody blocks DR4 receptor against TRAIL induced apoptosis. Plastic immobilized antibody induces apoptosis in sensitive cells. -
Clonality
Monoclonal -
Clone number
DR-4-02 -
Isotype
IgG1 -
Research areas
