Etomoxir (sodium salt), Carnitine palmitoyltransferase inhibitor (ab254445)
Key features and details
- Irreversible inhibitor of mitochondrial CPT1; PPARα direct agonist
- CAS Number: 828934-41-4
- Purity: > 98%
Soluble in DMSO to 10 mM with warming
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Etomoxir (sodium salt), Carnitine palmitoyltransferase inhibitor -
Description
Irreversible inhibitor of mitochondrial CPT1; PPARα direct agonist -
Alternative names
- (+)-Etomoxir sodium salt hydrate
- (R)-(+)-Etomoxir Na
- Etomoxir (Na salt)
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Biological description
Irreverisble inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1). PPARα direct agonist. Used in fatty acid oxidation studies. Induces ROS production in T cells with concentrations larger than 5µM and prevents T cell differentiation. Complex I of electron transport chain inhibited at concentration 200µM.
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Purity
> 98% -
General notes
Solutions in DMSO may be stored at -20°C for up to 1 month.
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CAS Number
828934-41-4 -
Chemical structure
Properties
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Chemical name
Sodium (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate
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Molecular weight
320.75 -
Molecular formula
C15H18ClNaO4 -
PubChem identifier
57345784 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM with warming
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Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1[C@](O1)(CCCCCCOC2=CC=C(C=C2)Cl)C(=O)[O-].[Na+] -
Source
Synthetic
