Estramustine phosphate sodium, antimitotic, antitumour agent (ab142747)
Key features and details
- Antimitotic, antitumour agent
- CAS Number: 52205-73-9
- Purity: > 95%
- Soluble in water to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Estramustine phosphate sodium, antimitotic, antitumour agent -
Description
Antimitotic, antitumour agent -
Biological description
Antimitotic, antitumour agent. Nor-nitrogen mustard conjugate of estradiol (Asc 657). Selective for prostate cells. Interferes with microtubule dynamics and reduces plasma levels of testosterone. Shows antineoplastic effects in vivo. Orally active. -
Purity
> 95% -
CAS Number
52205-73-9 -
Chemical structure
Properties
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Chemical name
Disodium [3-[bis(2-chloroethyl)carbamoyloxy]-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] phosphate -
Molecular weight
564.35 -
Molecular formula
C23H30Cl2NNa2O6P -
PubChem identifier
53395146 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+] -
Source
Synthetic
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Research areas
