Esculetin, lipoxygenase inhibitor (ab142873)
Key features and details
- Potent, selective and non-competitive lipoxygenase inhibitor
- CAS Number: 305-01-1
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Esculetin, lipoxygenase inhibitor -
Description
Potent, selective and non-competitive lipoxygenase inhibitor -
Biological description
Potent, selective and non-competitive lipoxygenase inhibitor (IC50 = 650 nM). Inhibits cell proliferation in tumor cells in vitro (IC50 = 193 μM). Suppresses MMP-9 expression in vitro. Antioxidant and antitumor agent. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
305-01-1 -
Chemical structure
Properties
-
Chemical name
6,7-Dihydroxychromen-2-one -
Molecular weight
178.14 -
Molecular formula
C9H6O4 -
PubChem identifier
5281416 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1=CC(=O)OC2=CC(=C(C=C21)O)O -
Source
Synthetic
-
Research areas
