EPZ015866 (GSK591), arginine methyltransferase PRMT5/MEP50 complex inhibitor (ab223597)
Key features and details
- Potent, selective inhibitor of the arginine methyltransferase PRMT5/MEP50 complex.
- CAS Number: 1616391-87-7
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
EPZ015866 (GSK591), arginine methyltransferase PRMT5/MEP50 complex inhibitor -
Description
Potent, selective inhibitor of the arginine methyltransferase PRMT5/MEP50 complex. -
Alternative names
- GSK591
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Purity
> 98% -
General notes
Protect from air.
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CAS Number
1616391-87-7 -
Chemical structure
Properties
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Chemical name
(S)-2-(Cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide -
Molecular weight
380.50 -
Molecular formula
C22H28N4O2 -
PubChem identifier
117072552 -
Storage instructions
Shipped at 4°C. Store at -20°C or -80°C. Store In the Dark. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC(C1)NC2=NC=CC(=C2)C(=O)NC[C@@H](CN3CCC4=CC=CC=C4C3)O -
Source
Synthetic