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Neuroscience Cell Adhesion Proteins Membrane Proteins

Epothilone B, Microtubule stabilizing agent (ab141271)

Price and availability

167 520 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Microtubule stabilizing agent
  • CAS Number: 152044-54-7
  • Purity: > 98%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Epothilone B, Microtubule stabilizing agent
  • Description

    Microtubule stabilizing agent
  • Biological description

    Microtubule-stabilizing agent. Analog of Epothilone A and D (ab143615 and ab143616). Displays highest efficacy in class III β-tubulin overexpressing malignancies. Inhibits Paclitaxel (ab120143)-resistant cell lines. Shows antitumor effects in vivo. Orally active.

  • Purity

    > 98%
  • CAS Number

    152044-54-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • Molecular weight

    507.68
  • Molecular formula

    C27H41NO6S
  • PubChem identifier

    448013
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cc3nc(/C=C(\C)[C@@H]1C[C@@H]2O[C@]2(C)CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1)cs3
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Cell Adhesion Proteins
    • Membrane Proteins
    • Neuroscience
    • Cell Type Marker
    • Glia marker
    • Oligodendrocyte marker
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Tags & Cell Markers
    • Cell Type Markers
    • Neuroscience Markers
    • Glial
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Transcription Factors
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Orphan Nuclear Receptors
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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