Emodin, 11beta-HSD1 inhibitor (ab141454)
Key features and details
- Potent 11β-HSD1 inhibitor. Antioxidant agent.
- CAS Number: 518-82-1
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Emodin, 11beta-HSD1 inhibitor -
Description
Potent 11β-HSD1 inhibitor. Antioxidant agent. -
Biological description
Potent, selective 11β-HSD1 inhibitor (IC50 values are 186 and 86 nM for human and mouse 11beta-HSD1 respectively). Antioxidant agent. Activates caspase-3, -8 and -9. Increases Bax and decreases Bcl-2. Antidyslipidemic in vivo. Orally active.
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Purity
> 98% -
CAS Number
518-82-1 -
Chemical structure
Properties
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Chemical name
1,3,8-Trihydroxy-6-methylanthracene-9,10-dione -
Molecular weight
270.24 -
Molecular formula
C15H10O5 -
PubChem identifier
3220 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
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SMILES
CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O -
Source
Synthetic
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Research areas
