Elastase Substrate, Fluorogenic (MeOSuc-AAPV-AFC) (ab142178)
Key features and details
- Highly sensitive coumarin-fluorogenic substrate for neutrophil elastase
- Purity: > 99%
Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Elastase Substrate, Fluorogenic (MeOSuc-AAPV-AFC) -
Description
Highly sensitive coumarin-fluorogenic substrate for neutrophil elastase -
Biological description
Highly sensitive coumarin-fluorogenic substrate for neutrophil elastase (Km =130 µM for leukocyte elastase). Compatible with in vitro assays with purified enzyme, on live cells, or in conditioned medium. The excitation wavelength is 380 nm and the emission wavelength is 500 nm.
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Purity
> 99% -
Chemical structure
Properties
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Chemical name
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-7-amino-4-trifluormethylcoumarin
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Molecular weight
681.67 -
Molecular formula
C31H38F3N5O9 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(OC)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3c(c2)OC(=O)C=C3C(F)(F)F -
Source
Synthetic
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Research areas
