DPQ (DMSO solution), PARP-1 inhibitor (ab146611)
Key features and details
- Potent, selective PARP-1 inhibitor
- CAS Number: 129075-73-6
- Purity: > 98%
- Supplied in DMSO (10 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
DPQ (DMSO solution), PARP-1 inhibitor -
Description
Potent, selective PARP-1 inhibitor -
Biological description
Potent, selective PARP-1 inhibitor (IC50 = 37 nM). Inhibits NF-κB signaling. Shows anti-inflammatory effects in vivo.
Also available as a solid (ab141461). -
Purity
> 98% -
CAS Number
129075-73-6 -
Chemical structure
Properties
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Chemical name
5-(4-Piperidin-1-ylbutoxy)-3,4-dihydro-2H-isoquinolin-1-one -
Molecular weight
302.41 -
Molecular formula
C18H26N2O2 -
PubChem identifier
9948349 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (10 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CCN(CC1)CCCCOC2=CC=CC3=C2CCNC3=O -
Source
Synthetic
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Research areas
