Doxifluridine (5'-Deoxy-5-fluorouridine), fluoropyrimidine antitumor (ab142295)
Key features and details
- Fluoropyrimidine antitumor and antiangiogenic agent
- CAS Number: 3094-09-5
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Doxifluridine (5'-Deoxy-5-fluorouridine), fluoropyrimidine antitumor -
Description
Fluoropyrimidine antitumor and antiangiogenic agent -
Biological description
Fluoropyrimidine. Shows antitumor and antiangiogenic effects in vivo. Activates NF-κB in macrophages. Orally active. Active metabolite 5-fluorouracil (ab142387) also available. -
Purity
> 98% -
CAS Number
3094-09-5 -
Chemical structure
Properties
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Chemical name
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione -
Molecular weight
246.19 -
Molecular formula
C9H11FN2O5 -
PubChem identifier
18343 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O -
Source
Synthetic
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Research areas