Cyclosporin D, TPA/PMA inhibitor (ab141922)
Key features and details
- TPA/PMA inhibitor with multiple biological activities
- CAS Number: 63775-96-2
- Purity: > 98%
- Soluble in ethanol
- Form / State: Solid
- Source: Fusarium solani
Overview
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Product name
Cyclosporin D, TPA/PMA inhibitor -
Description
TPA/PMA inhibitor with multiple biological activities -
Biological description
TPA/PMA inhibitor with multiple biological activities. Inhibitor of Ca2+/calmodulin dependent EF2 phosphorylation. Potent inhibitor of P. falciparum growth (IC50 = 32 nM). Anti-malariant and weak immunosuppressant. Active in vivo. -
Purity
> 98% -
CAS Number
63775-96-2 -
Chemical structure
Properties
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Molecular weight
1216.64 -
Molecular formula
C63H113N11O12 -
PubChem identifier
6436250 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC=CCC(C)C(C1C(=O)NC(C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)C)O -
Source
Fusarium solani
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Research areas
