Dihydroartemisinin, active metabolite of artemether and artesunate (ab142690)
Key features and details
- Induces cell cycle arrest and inhibits cell migration in cancer cells
- CAS Number: 71939-50-9
- Purity: > 96%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dihydroartemisinin, active metabolite of artemether and artesunate -
Description
Induces cell cycle arrest and inhibits cell migration in cancer cells -
Biological description
Induces cell cycle arrest and inhibits cell migration in cancer cells. Depletes cellular iron via transferrin receptor 1. Antimalarial and antitumor agent. Orally active. Active in vivo and in vitro. -
Purity
> 96% -
CAS Number
71939-50-9 -
Chemical structure
Properties
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Chemical name
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol -
Molecular weight
284.35 -
Molecular formula
C15H24O5 -
PubChem identifier
107770 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C -
Source
Synthetic
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Research areas
