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Cancer Drug resistance Topoisomerases

6-Aminonicotinamide, 6-phosphogluconate dehydrogenase inhibitor (ab142388)

Key features and details

  • 6-phosphogluconate dehydrogenase inhibitor
  • CAS Number: 329-89-5
  • Purity: > 96%
  • Soluble in DMSO to 5 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    6-Aminonicotinamide, 6-phosphogluconate dehydrogenase inhibitor
  • Description

    6-phosphogluconate dehydrogenase inhibitor
  • Biological description

    6-phosphogluconate dehydrogenase inhibitor (Ki = 0.46 μM). Interferes with glycolysis, resulting in ATP depletion. Active in vivo.
  • Purity

    > 96%
  • CAS Number

    329-89-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Aminopyridine-3-carboxamide
  • Molecular weight

    137.14
  • Molecular formula

    C6H7N3O
  • PubChem identifier

    9500
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 5 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=NC=C1C(=O)N)N
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Synthesis
    • Topoisomerases
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Corticoid
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Transcription Factors
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Dehydrogenase
    • Inhibitors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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