Dibutyryl-cGMP, cGMP analog (ab145203)
Key features and details
- Cell-permeable cGMP analog
- CAS Number: 51116-00-8
- Purity: > 96%
- Soluble in water to 100 mM and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dibutyryl-cGMP, cGMP analog -
Description
Cell-permeable cGMP analog -
Biological description
Cell-permeable cGMP analog. Activates Protein Kinase G (PKG). Raises intracellular Ca2+ concentrations similar to 8-Br-cGMP (ab141449). Shows antinociceptive effects in vivo. -
Purity
> 96% -
CAS Number
51116-00-8 -
Chemical structure
Properties
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Chemical name
[6-[2-(Butanoylamino)-6-oxo-3H-purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate sodium salt -
Molecular weight
507.37 -
Molecular formula
C18H23NaN5O9P -
PubChem identifier
44134671 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCC(=O)NC1=NC(=O)C2=C(N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+] -
Source
Synthetic
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Research areas
