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Biochemicals Product Range New

Asperosaponin VI (Akebia Saponin D), triterpene saponin  (ab143574)

Key features and details

  • Anti-inflammatory, antioxidant agent
  • CAS Number: 39524-08-8
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Asperosaponin VI (Akebia Saponin D), triterpene saponin 
  • Description

    Anti-inflammatory, antioxidant agent
  • Alternative names

    • Akebia Saponin D
  • Biological description

    Anti-inflammatory, antioxidant agent. Inhibits Akt and IκB kinase phosphorylation and NF-κB activation. Lowers creatine kinase-MB, lactate dehydrogenase and glutamic oxaloacetic transaminase levels. Increases glutathione peroxidase and SOD levels. Attenuates amyloid-β cytotoxicity. Shows anti-ischemic and anti-inflammatory effects in vivo.
  • Purity

    > 98%
  • CAS Number

    39524-08-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-[[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (6aR,6aS,6bR,8aR,9R,10S,12aR,14bR)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-3,4,4a,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4-carboxylate
  • Molecular weight

    929.10
  • Molecular formula

    C47H76O18
  • PubChem identifier

    71571505
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1(CC2C(CCC3(C2=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C)C(C1)C(=O)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Nitric oxide & oxidative stress
    • Antioxidants
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Akt
    • Inhibitors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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