D-erythro C8 Ceramide-1-phosphate, analog of endogenous ceramide-1-phosphate (ab141749)
Key features and details
- Cell-permeable analog of endogenous ceramide-1-phosphate
- CAS Number: 158983-53-0
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
D-erythro C8 Ceramide-1-phosphate, analog of endogenous ceramide-1-phosphate -
Description
Cell-permeable analog of endogenous ceramide-1-phosphate -
Biological description
Cell-permeable analog of endogenous ceramide-1-phosphate, a putative second messenger of sphingomyelin metabolism. Stimulates DNA synthesis and cell division in fibroblasts. Negative regulator of TNF-α production. Promotes Ca2+ entry through VGCCs in pituitary cells. -
Purity
> 98% -
General notes
Appperance: white to off-white solid or thin film
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CAS Number
158983-53-0 -
Chemical structure
Properties
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Chemical name
[3-Hydroxy-2-(octanoylamino)octadec-4-enyl] dihydrogen phosphate -
Molecular weight
505.70 -
Molecular formula
C26H52NO6P -
PubChem identifier
4465356 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCCCCC=CC(C(COP(=O)(O)O)NC(=O)CCCCCCC)O -
Source
Synthetic
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Research areas
