Cyclosporin H, TPA/PMA inhibitor (ab141923)
Key features and details
- TPA/PMA inhibitor
- CAS Number: 83602-39-5
- Purity: > 96%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Fusarium solani
Overview
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Product name
Cyclosporin H, TPA/PMA inhibitor -
Description
TPA/PMA inhibitor -
Biological description
TPA/PMA inhibitor. Selective inhibitor of formyl peptide receptors (Ki = 0.1 µM). Inhibits Ca2+/calmodulin dependent EF-2 phosphorylation. Inhibits FMLP-induced superoxide anion formation (IC50 = 40 nM). Multiple biological effects. -
Purity
> 96% -
CAS Number
83602-39-5 -
Chemical structure
Properties
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Molecular weight
1202.61 -
Molecular formula
C62H111N11O12 -
PubChem identifier
6436249 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC1C(=O)N(CC(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)C)CC(C)C)C)C -
Source
Fusarium solani
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Research areas
