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Neuroscience Neurotransmitter Biogenic Amines Dopamine

Curcumin (high purity), Lipoxygenase and COX inhibitor (ab141921)

Key features and details

  • High purity. Lipoxygenase and COX inhibitor
  • CAS Number: 458-37-7
  • Purity: > 98%
  • Soluble in DMSO to 10 mM and in ethanol to 10 mM
  • Form / State: Solid
  • Source: Curcuma longa

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Overview

  • Product name

    Curcumin (high purity), Lipoxygenase and COX inhibitor
  • Description

    High purity. Lipoxygenase and COX inhibitor
  • Biological description

    High purity flavonoid derivative. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC50 values are 8 and 52 μM, respectively). Shows diverse range of actions including free radical scavenging activity, cardio and neuroprotective effects. Blood brain barrier permeable. Active in vitro and in vivo
  • Purity

    > 98%
  • CAS Number

    458-37-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • Molecular weight

    368.38
  • Molecular formula

    C21H20O6
  • PubChem identifier

    969516
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
  • Source

    Curcuma longa

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Serotonin / 5HT
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Alzheimer's disease
    • Amyloid
    • Cardiovascular
    • Blood
    • Coagulation
    • Extrinsic
    • Cardiovascular
    • Blood
    • Coagulation
    • Common
    • Cardiovascular
    • Angiogenesis
    • Angiogenic Factors
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Signal Transduction
    • Metabolism
    • Mitochondrial
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Other Amines
    • Cancer
    • Growth factors
    • Hormones
    • Kits/ Lysates/ Other
    • Kits
    • ELISA Kits
    • ELISA Kits
    • CD markers ELISA kits
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Cyclooxygenase
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Mitochondrial markers
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Cholesterol Metabolism
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • Transcription factors
    • Biochemicals
    • Research Area
    • Cancer
    • DNA, RNA & protein synthesis
    • Transcription factors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

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