COG 133, apolipoprotein peptide fragment (ab269699)
Key features and details
- ApoE peptide mimetic.
- CAS Number: 514200-66-9
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
COG 133, apolipoprotein peptide fragment -
Description
ApoE peptide mimetic. -
Biological description
ApoE peptide mimetic. Corresponds to amino acids 133-149 of human ApoE. Non-cometitive alpha-7 nicotinic acetylcholine receptor antagonist (IC50 = 445 nM). Inhibits NMDA receptor channel function via interaction with the low-density lipoprotein receptor-related protein. Reduces inflammation, demyleination and cellular infiltration in animal models of multiple sclerosis. Reduces markers of inflammation in 5-fluorouracil model of intestinal mucositis.
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CAS Number
514200-66-9 -
Chemical structure
Properties
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Molecular weight
2169.73 -
Molecular formula
C97H181N37O19 -
Sequence
LRVRLASHLRKLRKRLL -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
Images
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Chemical Structure - COG 133, apolipoprotein peptide fragment (ab269699)
Chemical structure of COG 133, apolipoprotein peptide fragment, 514200-66-9