CGK 733, ATR and ATM kinase inhibitor (ab144816)
Key features and details
- Selective ATR and ATM kinase inhibitor
- CAS Number: 905973-89-9
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CGK 733, ATR and ATM kinase inhibitor -
Description
Selective ATR and ATM kinase inhibitor -
Biological description
Selective ATR and ATM kinase inhibitor. Shows antiproliferative effects in a range of cancer cell lines. Blocks recruitment and hyperphosphorylation of RPA2. -
Purity
> 99% -
CAS Number
905973-89-9 -
Chemical structure
Properties
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Chemical name
2,2-Diphenyl-N-[2,2,2-trichloro-1-[(4-fluoro-3-nitrophenyl)carbamothioylamino]ethyl]acetamide -
Molecular weight
555.84 -
Molecular formula
C23H18Cl3FN4O3S -
PubChem identifier
6605258 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
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SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-] -
Source
Synthetic
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Research areas
