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Biochemicals Product Range New

CAY10621 (SKI 5C), SPHK 1 inhibitor (ab144410)

Key features and details

  • Selective SPHK 1 inhibitor
  • CAS Number: 120005-55-2
  • Purity: > 98%
  • Soluble in DMSO to 5 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CAY10621 (SKI 5C), SPHK 1 inhibitor
  • Description

    Selective SPHK 1 inhibitor
  • Alternative names

    • SKI 5C
  • Biological description

    Selective SPHK 1 inhibitor (IC50 = 3.3 μM). Induces cell cycle arrest in sub-G1 phase. Shows antiproliferative effects. Inhibits ERK1/2 and AKT signaling. Shows antitumor effects in vivo.
  • Purity

    > 98%
  • CAS Number

    120005-55-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    tert-Butyl (4S)-4-hexadec-2-ynoyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
  • Molecular weight

    435.65
  • Molecular formula

    C26H45NO4
  • PubChem identifier

    11305122
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 5 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCC#CC(=O)[C@@H]1COC(N1C(=O)OC(C)(C)C)(C)C
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • MAPK
    • ERK
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Sphingosine kinase
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • PI3K/Akt signaling
    • Inhibitors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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