CAY10621 (SKI 5C), SPHK 1 inhibitor (ab144410)
Key features and details
- Selective SPHK 1 inhibitor
- CAS Number: 120005-55-2
- Purity: > 98%
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CAY10621 (SKI 5C), SPHK 1 inhibitor -
Description
Selective SPHK 1 inhibitor -
Alternative names
- SKI 5C
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Biological description
Selective SPHK 1 inhibitor (IC50 = 3.3 μM). Induces cell cycle arrest in sub-G1 phase. Shows antiproliferative effects. Inhibits ERK1/2 and AKT signaling. Shows antitumor effects in vivo. -
Purity
> 98% -
CAS Number
120005-55-2 -
Chemical structure
Properties
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Chemical name
tert-Butyl (4S)-4-hexadec-2-ynoyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate -
Molecular weight
435.65 -
Molecular formula
C26H45NO4 -
PubChem identifier
11305122 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCCCCC#CC(=O)[C@@H]1COC(N1C(=O)OC(C)(C)C)(C)C -
Source
Synthetic
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Research areas