Nemadipine A, L-type calcium channel protein inhibitor (ab145991)
Key features and details
- Cell-permeable L-type calcium channel protein inhibitor
- CAS Number: 54280-71-6
- Purity: > 97%
- Soluble in ethanol to 25 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Nemadipine A, L-type calcium channel protein inhibitor -
Description
Cell-permeable L-type calcium channel protein inhibitor -
Biological description
Cell-permeable L-type calcium channel protein inhibitor. Antagonizes α1-subunit of L-type calcium channel. Sensitizes cancer cells to TRAIL-induced apoptosis. 1,4-dihydropyridine (DHP) analog. -
Purity
> 97% -
CAS Number
54280-71-6 -
Chemical structure
Properties
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Chemical name
Diethyl 2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate -
Molecular weight
419.35 -
Molecular formula
C19H18F5NO4 -
PubChem identifier
2856102 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 25 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)C1=C(NC(=C(C1C2=C(C(=C(C(=C2F)F)F)F)F)C(=O)OCC)C)C -
Source
Synthetic
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Research areas