Calpeptin, cell-permeable calpain inhibitor (ab120804)
Key features and details
- Potent, cell-permeable calpain inhibitor
- CAS Number: 117591-20-5
- Purity: > 98%
- Soluble in ethanol to 100 mM and in DMSO to 100mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Calpeptin, cell-permeable calpain inhibitor -
Description
Potent, cell-permeable calpain inhibitor -
Biological description
Potent, cell-permeable calpain inhibitor, a Ca2+-dependent protease. Ki values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier.
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Purity
> 98% -
CAS Number
117591-20-5 -
Chemical structure
Properties
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Molecular weight
362.47 -
Molecular formula
C20H30N2O4 -
Sequence
LX (Modifications: N-terminal benzyloxycarbonyl; X-2 = Nle) -
PubChem identifier
73364 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1 -
Source
Synthetic
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Research areas