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Caged MK 801, NMDA receptor open-channel blocker (ab146431)

Price and availability

278 083 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. Uncaged by UV light.
  • CAS Number: 217176-91-5
  • Purity: > 99%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Caged MK 801, NMDA receptor open-channel blocker
  • Description

    Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. Uncaged by UV light.
  • Biological description

    Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. UV-active MK 801 (ab144485, ab120027, ab120028) analog. Shows anticonvulsant effects in vivo.

  • Purity

    > 99%
  • CAS Number

    217176-91-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5S,10R)-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
  • Molecular weight

    460.49
  • Molecular formula

    C26H24N2O6
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    [O-][N+](=O)c5cc(OC)c(OC)cc5COC(=O)N4[C@@H]3Cc1ccccc1[C@@]4(C)c2ccccc23
  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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