Butein, c-Met and EGFR tyrosine kinase inhibitor (ab144511)
Key features and details
- Dual c-Met and EGFR tyrosine kinase inhibitor
- CAS Number: 487-52-5
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Butein, c-Met and EGFR tyrosine kinase inhibitor -
Description
Dual c-Met and EGFR tyrosine kinase inhibitor -
Biological description
Dual c-Met and EGFR tyrosine kinase inhibitor. Inhibits MMP-9 expression and activity. Suppresses tumor cell invasion. Induces apoptosis. Shows anti-adipogenic effects. Shows antimetastatic and antitumor effects in vivo. -
Purity
> 98% -
CAS Number
487-52-5 -
Chemical structure
Properties
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Chemical name
(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one -
Molecular weight
272.26 -
Molecular formula
C15H12O5 -
PubChem identifier
5281222 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=C(C=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O)O -
Source
Synthetic
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Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
