Buspirone hydrochloride, 5-HT1A agonist (ab120420)
Key features and details
- 5-HT1A agonist. Anxiolytic.
- CAS Number: 33386-08-2
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Buspirone hydrochloride, 5-HT1A agonist -
Description
5-HT1A agonist. Anxiolytic. -
Biological description
5-HT1A partial agonist (Ki = 9.3 - 29.5 nM). Anxiolytic in vivo. Many reported effects including actions on dopaminergic and noradrenergic pathways, as well as the GABA-benzodiazepine receptor chloride ionophore complex.
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Purity
> 99% -
CAS Number
33386-08-2 -
Chemical structure
Properties
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Chemical name
N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride -
Molecular weight
421.97 -
Molecular formula
C21H31N5O2.HCl -
PubChem identifier
36431 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.O=C4CC1(CCCC1)CC(=O)N4CCCCN2CCN(CC2)c3ncccn3 -
Source
Synthetic
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Research areas