BU 224 hydrochloride, Imidazoline I2 binding site allosteric modulator (ab146415)
Key features and details
- High affinity Imidazoline I2 binding site allosteric modulator
- CAS Number: 205437-64-5
- Purity: > 99%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BU 224 hydrochloride, Imidazoline I2 binding site allosteric modulator -
Description
High affinity Imidazoline I2 binding site allosteric modulator -
Biological description
High affinity Imidazoline I2 binding site allosteric modulator (Ki = 2.1 nM). Dose-dependently inhibits C-fiber evoked responses, post-discharge and wind-up. Shows antinociceptive effects in vivo.
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Purity
> 99% -
CAS Number
205437-64-5 -
Chemical structure
Properties
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Chemical name
2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride -
Molecular weight
233.70 -
Molecular formula
C12H11N3.HCl -
PubChem identifier
11957470 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl -
Source
Synthetic
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Research areas