CF405M Anti-CD105 antibody [2H6F11], prediluted (ab123634)
![CF405M Anti-CD105 antibody [2H6F11], prediluted (ab123634)](https://www.abcam.com/ps/products/123/ab123634/Images/CD105-Primary-antibodies-ab123634-1.jpg "CF405M Anti-CD105 antibody [2H6F11], prediluted (ab123634)")
Key features and details
- CF405M Mouse monoclonal [2H6F11] to CD105, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: CF405M. Ex: 408nm, Em: 452nm
- Isotype: IgG1
Overview
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Product name
CF405M Anti-CD105 antibody [2H6F11], prediluted
See all CD105 primary antibodies -
Description
CF405M Mouse monoclonal [2H6F11] to CD105, prediluted -
Host species
Mouse -
Conjugation
CF405M. Ex: 408nm, Em: 452nm -
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Human
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Immunogen
Human Endoglin fusion protein.
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Positive control
- Nalm-6 cell line
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General notes
CD105 is a component of the TGF-B receptor system and can bind TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. CD105 is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta, Pre-B cells in fetal marrow, erythroid precursors in fetal and adult bone marrow and is weakly expressed by stromal fibroblasts. U937 cells and monocytes and tissue macrophages also expresses weakly CD105. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumours, or in cases of wound healing or dermal inflammation.
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
CD105 is a component of the TGF-B receptor system and can bind TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. CD105 is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta, Pre-B cells in fetal marrow, erythroid precursors in fetal and adult bone marrow and is weakly expressed by stromal fibroblasts. U937 cells and monocytes and tissue macrophages also expresses weakly CD105. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumours, or in cases of wound healing or dermal inflammation. -
Clonality
Monoclonal -
Clone number
2H6F11 -
Isotype
IgG1 -
Research areas
Images
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Flow Cytometry - CF405M Anti-CD105 antibody [2H6F11], prediluted (ab123634)Staining of Nalm-6 cell line with ab123634 at 5 µl/106 cells and isotype control IgG1 CFBlue. Total cells were used for analysis.
