Bromopyruvic acid (3-bromopyruvic acid), Hexokinase II inhibitor (ab146138)
Key features and details
- Hexokinase II inhibitor. Antiumor agent.
- CAS Number: 1113-59-3
- Soluble in water to 100 mM and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bromopyruvic acid (3-bromopyruvic acid), Hexokinase II inhibitor -
Description
Hexokinase II inhibitor. Antiumor agent. -
Alternative names
- 3-bromopyruvic acid
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Biological description
Hexokinase II inhibitor. Antitumor agent. Inhibits glutathione S-transferase and SOD. Pyruvic acid (ab145036) derivative. Induces oxidative stress. Induces S and G2/M cell cycle arrest. Shows antiproliferative effects. Shows antitumor and antimicrobial effects in vivo. -
CAS Number
1113-59-3 -
Chemical structure
Properties
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Chemical name
3-Bromo-2-oxopropanoic acid -
Molecular weight
166.96 -
Molecular formula
C3H3BrO3 -
PubChem identifier
70684 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C(C(=O)C(=O)O)Br -
Source
Synthetic
