Lofexidine hydrochloride, alpha2-adrenoceptor agonist (ab142906)
Key features and details
- Selective α2-adrenoceptor agonist
- CAS Number: 21498-08-8
- Purity: > 98%
- Soluble in water and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Lofexidine hydrochloride, alpha2-adrenoceptor agonist -
Description
Selective α2-adrenoceptor agonist -
Biological description
Selective α2-adrenoceptor agonist (EC50 = 14 μM). Structurally related to clonidine hydrochloride (Asc 753). Shows short-acting antisympathetic and centrally-mediated antiaddiction behavioural effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
21498-08-8 -
Chemical structure
Properties
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Chemical name
2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride -
Molecular weight
295.60 -
Molecular formula
C11H12Cl2N2O.HCl -
PubChem identifier
30667 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl -
Source
Synthetic
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Research areas
