Biotin Gold Conjugate (40nm, 10 OD) (ab186922) is a unique coated nanoparticle that has an avidly bound protective surface coat which can withstand the most extreme conditions (e.g. 2.5M NaOH at 70°C for ~2 hours).

By covalently attaching biotin ligand to the surface coat the resulting Gold-Biotin nanoparticles inherit the stability attributes of the core nanoparticle; moreover the biotin ligand cannot desorb, which is a major problem with all competing products in which a biotin analogue is directly attached to the metal. Biotin is attached to Gold via an extended linker to facilitate high affinity molecular interactions with avidin and streptavidin. 

A common application for Gold Biotin is to be used as a detector in Lateral Flow Assays (LFAs).

Notes:

This product is manufactured by Expedeon, an Abcam company. It was previously called 40nm InnovaCoat® GOLD (10 OD) Biotin Conjugate. Expedeon product code 240-0200 is the same as the 200 µL size of this product and code 240-1000 is the same as the 1 mL size.

Abcam has not and does not intend to apply for the REACH Authorisation of customers’ uses of products that contain European Authorisation list (Annex XIV) substances.

It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.