Bestatin, aminopeptidase inhibitor (ab141417)
Key features and details
- Potent, competitive aminopeptidase inhibitor
- CAS Number: 58970-76-6
- Purity: > 99%
- Soluble in DMSO to 5 mM. Soluble in 1 N NaOH to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bestatin, aminopeptidase inhibitor -
Description
Potent, competitive aminopeptidase inhibitor -
Biological description
Potent, competitive aminopeptidase inhibitor (IC50 values are 20 and 60 nM for leucine aminopeptidase and aminopeptidase B, respectively). Inhibits leukotriene A4 hydrolase and tumor cell proliferation. Shows immunomodulatory effects in vivo. Orally active. -
Purity
> 99% -
CAS Number
58970-76-6 -
Chemical structure
Properties
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Chemical name
(2S)-2-[[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid -
Molecular weight
308.38 -
Molecular formula
C16H24N2O4 -
PubChem identifier
72172 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM. Soluble in 1 N NaOH to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O -
Source
Synthetic
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Research areas
