Avarol, leukotriene B4 inhibitor (ab144200)
Key features and details
- Potent leukotriene B4 inhibitor. Anti-inflammatory agent.
- CAS Number: 55303-98-5
- Purity: > 97%
- Soluble in ethanol and DMSO
- Form / State: Solid
- Source: Dysidea avara
Overview
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Product name
Avarol, leukotriene B4 inhibitor -
Description
Potent leukotriene B4 inhibitor. Anti-inflammatory agent. -
Biological description
Potent leukotriene B4 inhibitor (IC50 = 0.6 μM). Anti-inflammatory agent. Inhibits TNF-α (IC50 = 1 μM) and NFκB. Inhibits thromboxane B2 release and phospholipase A2 activity (IC50 values are 1.4 and 158 μM respectively). Shows antibacterial, antifungal and anti-inflammatory effects in vivo. -
Purity
> 97% -
CAS Number
55303-98-5 -
Chemical structure
Properties
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Chemical name
2-[[(1R,2S,4aS,8aS)-1,2,4a,5-Tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol -
Molecular weight
314.46 -
Molecular formula
C21H30O2 -
PubChem identifier
72185 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in ethanol and DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C=CC(=C3)O)O)CCC=C2C)C -
Source
Dysidea avara
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Research areas