Vecuronium bromide, Competitive nicotinic acetylcholine receptor antagonist (ab120536)
Key features and details
- Competitive nicotinic acetylcholine receptor (nAChR) antagonist
- CAS Number: 50700-72-6
- Soluble in DMSO to 100 mM, in ethanol to 100 mM and in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Vecuronium bromide, Competitive nicotinic acetylcholine receptor antagonist -
Description
Competitive nicotinic acetylcholine receptor (nAChR) antagonist -
Biological description
Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.
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CAS Number
50700-72-6 -
Chemical structure
Properties
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Chemical name
1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide -
Molecular weight
637.74 -
Molecular formula
C34H57BrN2O4 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM, in ethanol to 100 mM and in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[Br-].C[N+]1(CCCCC1)C2C[C@H]3C4CC[C@H]5C[C@H](OC(C)=O)C(CC5(C)[C@H]4CCC3(C)C2OC(C)=O)N6CCCCC6 -
Source
Synthetic
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Research areas
