Auraptene, Activates PPARalpha and PPARgamma (ab141907)
Key features and details
- Activates PPARα and PPARγ. Modulates estrogen receptors
- CAS Number: 495-02-3
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Citrus sp.
Overview
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Product name
Auraptene, Activates PPARalpha and PPARgamma -
Description
Activates PPARα and PPARγ. Modulates estrogen receptors -
Biological description
Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
495-02-3 -
Chemical structure
Properties
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Chemical name
7-[(2E)-3,7-Dimethylocta-2,6-dienoxy]chromen-2-one -
Molecular weight
298.38 -
Molecular formula
C19H22O3 -
PubChem identifier
1550607 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C -
Source
Citrus sp.
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Research areas
