Aristoforin, SIRT1 and SIRT2 inhibitor (ab144509)
Key features and details
- Apoptotic agent. SIRT1 and SIRT2 inhibitor.
- CAS Number: 849215-53-8
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Aristoforin, SIRT1 and SIRT2 inhibitor -
Description
Apoptotic agent. SIRT1 and SIRT2 inhibitor. -
Biological description
SIRT1 and SIRT2 inhibitor. Apoptotic agent. Hyperforin (ab144276) derivative. Induces cell cycle arrest. Shows potent antitumor effects and inhibits lymphangiogenesis in vivo. -
Purity
> 95% -
CAS Number
849215-53-8 -
Chemical structure
Properties
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Chemical name
2-[[(1R,5R,6R,7S)-6-Methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-4,9-dioxobicyclo[3.3.1]non-2-en-2-yl]oxy]-acetic acid -
Molecular weight
594.80 -
Molecular formula
C37H54O6 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C(=O)[C@]21C(=O)C(C\C=C(/C)C)=C(OCC(=O)O)[C@](C[C@H](C\C=C(/C)C)[C@@]1(C)CC\C=C(/C)C)(C\C=C(/C)C)C2=O -
Source
Synthetic
