AR-R 17779 hydrochloride, alpha7 nAChR agonist (ab142817)
Key features and details
- Potent, selective α7 nAChR agonist
- CAS Number: 178419-42-6
Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AR-R 17779 hydrochloride, alpha7 nAChR agonist -
Description
Potent, selective α7 nAChR agonist -
Biological description
Potent, selective α7 nAChR agonist (EC50 = 420 nM). Shows excitatory central effects in vivo. Blood-brain barrier permeable.
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CAS Number
178419-42-6 -
Chemical structure
Properties
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Chemical name
(3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-one hydrochloride
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Molecular weight
218.68 -
Molecular formula
C9H14N2O2.HCl -
PubChem identifier
9859263 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.O=C3NC[C@@]2(CN1CCC2CC1)O3 -
Source
Synthetic
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Research areas
