Conduritol B Epoxide (Conduritol Epoxide), beta-glucosidase inhibitor (ab144118)
Key features and details
- Selective, irreversible β-glucosidase inhibitor
- CAS Number: 6090-95-5
- Purity: > 98%
- Soluble in water to 100 mM and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Conduritol B Epoxide (Conduritol Epoxide), beta-glucosidase inhibitor -
Description
Selective, irreversible β-glucosidase inhibitor -
Biological description
Selective, irreversible β-glucosidase inhibitor (IC50 values are 1 and 100 μM for β-glucosidase and α-glucosidase respectively). Upregulates CD1d expression by THP-1 cells. Raises intracellular glucosylceramide levels. Induces α-synuclein aggregation in the CNS in vivo. -
Purity
> 98% -
CAS Number
6090-95-5 -
Chemical structure
Properties
-
Chemical name
(1R,2R,3S,4S,5R,6S)-7-Oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol -
Molecular weight
162.14 -
Molecular formula
C6H10O5 -
PubChem identifier
119054 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
[C@@H]1([C@@H]([C@H]([C@H]2[C@@H]([C@@H]1O)O2)O)O)O -
Source
Synthetic
-
Research areas
