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Anti-SH3BP2 (phospho S427) antibody (ab2176)

Anti-SH3BP2 (phospho S427) antibody (ab2176)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Rabbit polyclonal to SH3BP2 (phospho S427)
  • Suitable for: WB, ELISA
  • Reacts with: Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-SH3BP2 (phospho S427) antibody
    See all SH3BP2 primary antibodies
  • Description

    Rabbit polyclonal to SH3BP2 (phospho S427)

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Host species

    Rabbit
  • Tested Applications & Species

    Application Species
    WB
    Human
    See all applications and species data
  • Immunogen

    Synthetic phospho peptide: SFRSFSpFEKPRQ, corresponding to amino acids 422-433 of Human SH3BP2.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • General notes


    Phosphorylation of SH3BP2 occurs on Ser 427 for activation. SH3BP2 mediates interactions of huntingtin and MLK2 (mixed lineage kinase).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 0.424% Potassium phosphate, 0.87% Sodium chloride
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Affinity purified chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
  • Primary antibody notes

    Phosphorylation of SH3BP2 occurs on Ser 427 for activation. SH3BP2 mediates interactions of huntingtin and MLK2 (mixed lineage kinase).
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Adapters
    • Cytoplasmic
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other

Images

  • Western blot - Anti-SH3BP2 (phospho S427) antibody (ab2176)
    Western blot - Anti-SH3BP2 (phospho S427) antibody (ab2176)
    Western blot analysis is shown using ab2176 to detect endogenous protein present in unstimulated human whole cell lysates.  The band as indicated by the arrowheads is evident in both M059 cells (panel A) and PC-3 cells (panel B).  Comparison to a molecular weight marker indicates a band of ~60 kDa that probably corresponds to human SH3BP2 protein.  The blot was incubated with a 1:500 dilution of the antibody at room temperature followed by detection using standard techniques. 

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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