Anti-Neuroligin 2 antibody (ab36602)
Key features and details
- Rabbit polyclonal to Neuroligin 2
- Suitable for: ELISA
- Isotype: IgG
Overview
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Product name
Anti-Neuroligin 2 antibody
See all Neuroligin 2 primary antibodies -
Description
Rabbit polyclonal to Neuroligin 2This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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Host species
Rabbit -
Species reactivity
Predicted to work with: Mouse, Rat, Human
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Immunogen
Synthetic peptide corresponding to Human Neuroligin 2 aa 650-750 conjugated to keyhole limpet haemocyanin.
(Peptide available asab36601)
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
Application Abreviews Notes ELISA Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab36601).Notes ELISA
Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab36601).Target
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Relevance
Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini. -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 57555 Human
- Entrez Gene: 216856 Mouse
- Entrez Gene: 117096 Rat
- Omim: 606479 Human
- SwissProt: Q8NFZ4 Human
- SwissProt: Q69ZK9 Mouse
- SwissProt: Q62888 Rat
- Unigene: 26229 Human
see all -
Alternative names
- KIAA1366 antibody
- MGC67386 antibody
- NL2 antibody
see all
Datasheets and documents
References (2)
ab36602 has been referenced in 2 publications.
- Heshmati M et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proc Natl Acad Sci U S A 115:1111-1116 (2018). PubMed: 29339486
- Swaminathan A et al. Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Curr Biol 28:1924-1937.e5 (2018). PubMed: 29861134
