Idoxuridine, Antiviral thymidine analog (ab142581)
Key features and details
- Antiviral thymidine analog Radiosensitizer. Anticancer
- CAS Number: 54-42-2
- Purity: > 98%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Idoxuridine, Antiviral thymidine analog -
Description
Antiviral thymidine analog Radiosensitizer. Anticancer -
Alternative names
- (+)-5-Iodo-2'-deoxyuridine
- IdU
-
Biological description
Selective cytotoxic cell-permeable anti-herpesvirus agent (IC50 = 4.3 μM). Radiosensitizing. Incorporates into DNA increases susceptibility of cancer cell to radiation damage. Active in vivo.
-
Purity
> 98% -
CAS Number
54-42-2 -
Chemical structure
Properties
-
Chemical name
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione -
Molecular weight
354.10 -
Molecular formula
C9H11IN2O5 -
PubChem identifier
5905 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O -
Source
Synthetic
-
Research areas
