Cinnabarinic acid, Endogenous mGlu4 selective agonist (ab120506)
Key features and details
- Endogenous mGlu4 selective agonist
- CAS Number: 606-59-7
- Purity: > 98%
- Soluble in DMSO to 25 mM (requires warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cinnabarinic acid, Endogenous mGlu4 selective agonist -
Description
Endogenous mGlu4 selective agonist -
Biological description
Endogenous selective mGlu4 agonist; generated by autoxidation of the tryptophan metabolite 3-hydroxyanthranilic acid. Activates mGlu4 receptors in transiently transfected HEK293 cells, and is devoid of activity on other mGlu receptor subtypes (mGlu1, 2, 5, 6, 7, and 8). Protects against NMDA-induced excitotoxic cell death.
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Purity
> 98% -
CAS Number
606-59-7 -
Chemical structure
Properties
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Chemical name
2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid -
Molecular weight
300.23 -
Molecular formula
C14H8N2O6 -
PubChem identifier
114918 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM (requires warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=C2C(=C1)OC3=CC(=O)C(=C(C3=N2)C(=O)O)N)C(=O)O -
Source
Synthetic
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Research areas
