Antibodies, Proteins, Kits and Reagents for Life Science

274 732 ₸ Product size

100 µg 274 732 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-Dynamin 1 antibody
See all Dynamin 1 primary antibodies
Description

Rabbit polyclonal to Dynamin 1
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Mouse

See all applications and species data
Immunogen

Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
Positive control
- This antibody gave a positive signal in Human, Mouse and Rat Brain tissue lysates.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

Batches of this product that have a concentration
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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab108458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Mouse
All applications	Chicken Cow Dog Pig Chimpanzee Macaque monkey

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 97 kDa).

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 97 kDa).

Function

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Sequence similarities

Belongs to the dynamin family.
Contains 1 GED domain.
Contains 1 PH domain.
Cellular localization

Cytoplasm. Cytoplasm > cytoskeleton. Microtubule-associated.
Target information above from: UniProt accession Q05193 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 1759 Human
- Entrez Gene: 13429 Mouse
- Entrez Gene: 140694 Rat
- Omim: 602377 Human
- SwissProt: Q05193 Human
- SwissProt: P39053 Mouse
- SwissProt: P21575 Rat
- Unigene: 522413 Human
- Unigene: 44736 Mouse
- Unigene: 10354 Rat
see all
Alternative names
- B dynamin antibody
- D100 antibody
- DNM 1 antibody
- DNM antibody
- DNM1 antibody
- DYN1_HUMAN antibody
- Dynamin antibody
- Dynamin-1 antibody
- Dynamin1 antibody
see all

Publishing research using ab108458? Please let us know so that we can cite the reference in this datasheet.

ab108458 has been referenced in 2 publications.

Zhou W et al. Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis. Mol Hum Reprod 23:657-673 (2017). PubMed: 29044420
Zhou W et al. Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis. Biol Reprod 96:159-173 (2017). PubMed: 28395327