Anti-CRMP2 (phospho T509) antibody (ab192799)
Key features and details
- Rabbit polyclonal to CRMP2 (phospho T509)
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CRMP2 (phospho T509) antibody
See all CRMP2 primary antibodies -
Description
Rabbit polyclonal to CRMP2 (phospho T509) -
Host species
Rabbit -
Specificity
ab192799 detects endogenous levels of CRMP2 only when phosphorylated at Threonine 509. -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P HumanWB Human
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Immunogen
Synthetic peptide corresponding to Human CRMP2 (phospho T509) conjugated to Keyhole Limpet Haemocyanin (KLH). Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K).
Database link: Q16555 -
Positive control
- WB: HT29 cell extract; IHC: Human brain tissue.
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General notes
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 49% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab192799 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Images
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Western blot - Anti-CRMP2 (phospho T509) antibody (ab192799)All lanes : Anti-CRMP2 (phospho T509) antibody (ab192799) at 1/500 dilution
Lane 1 : HT29 cell extract
Lane 2 : HT29 cell extract with antigen-specific peptide
Predicted band size: 62 kDa
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP2 (phospho T509) antibody (ab192799)Immunohistochemical analysis of paraffin-embedded human brain tissue labeling CRMP2 (phospho T509) with ab192799 at 1/50 (left) or ab192799 preincubated with blocking peptide (right).
