Anti-C3 antibody [11H9]
See all C3 primary antibodies

Rat monoclonal [11H9] to C3

Rat

This antibody recognizes both intact C3 and its cleaved products C3b, iC3b, C3d and C3dg. The mature protein C3 has a molecular weight of approximately 190 kDa. The complement factor C3 consists of an alpha- and a beta-chain, linked by disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylotoxin and generating C3b (alpha chain and beta chain). C3b has a molecular weight of approximately 185 kDa. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. iC3b has a molecular weight of approximately 182 kDa. Does not cross react with C4.

Reacts with: Mouse
Does not react with: Human

C57BL/6 thymocytes saturated with rat anti-Thy-1 monoclonal antibody of IgG2b subclass (RmT1).

Liquid

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA

Protein G purified

0.2 µm filtered

Monoclonal

11H9

IgG2a

• Immunology
• Innate Immunity
• Complement
• Classical Pathway

• Neuroscience
• Cell Type Marker
• Neuron marker
• Synapse marker