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Epigenetics and Nuclear Signaling Transcription Domain Families Zinc Finger

Anti-Bcl6 antibody [rBCL6/1527] (ab238043)

Anti-Bcl6 antibody [rBCL6/1527] (ab238043)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Mouse monoclonal [rBCL6/1527] to Bcl6
  • Suitable for: Protein Array, IHC-P
  • Reacts with: Human

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Overview

  • Product name

    Anti-Bcl6 antibody [rBCL6/1527]
    See all Bcl6 primary antibodies
  • Description

    Mouse monoclonal [rBCL6/1527] to Bcl6
  • Host species

    Mouse
  • Tested Applications & Species

    Application Species
    IHC-P
    Human
    Protein Array
    Human
    See all applications and species data
  • Immunogen

    Recombinant fragment within Human Bcl-6 aa 256-389. The exact sequence is proprietary.
    Database link: P41182

  • Positive control

    • IHC-P: Human Hodgkin's lymphoma tissue.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

    Learn more here.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    Purified from Bioreactor Concentrate by Protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    rBCL6/1527
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Cancer susceptibility
    • Proto-oncogenes
    • Cancer
    • Oncoproteins/suppressors
    • Oncoproteins
    • Transcription factors
    • Epigenetics and Nuclear Signaling
    • ChIP assays
    • ChIP kits

Images

  • Protein Array - Anti-Bcl6 antibody [rBCL6/1527] (ab238043)
    Protein Array - Anti-Bcl6 antibody [rBCL6/1527] (ab238043)
    ab238043 was tested in protein array against over 19000 different full-length human proteins.
    Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
    A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bcl6 antibody [rBCL6/1527] (ab238043)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bcl6 antibody [rBCL6/1527] (ab238043)

    Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma tissue stained for Bcl-6 using ab238043 at 2 μg/ml in immunohistochemical analysis.

  • Anti-Bcl6 antibody [rBCL6/1527] (ab238043)
    Anti-Bcl6 antibody [rBCL6/1527] (ab238043)

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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