Anti-ALK antibody [SP8] (ab16670)
![Anti-ALK antibody [SP8] (ab16670)](https://www.abcam.com/ps/products/16/ab16670/Images/ab16670-249499-anti-alk-antibody-sp8-immunohistochemistry.jpg "Anti-ALK antibody [SP8] (ab16670)")
Key features and details
- Rabbit monoclonal [SP8] to ALK
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-ALK antibody [SP8]
See all ALK primary antibodies -
Description
Rabbit monoclonal [SP8] to ALK -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
-
Immunogen
Recombinant fragment within ALK aa 1350-1500. The exact sequence is proprietary.
-
Positive control
- Anaplastic lymphoma
-
General notes
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The amino acid sequence used to raise this antibody was: aa 1366-1468.
This antibody recognises a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of large cell lymphomas. This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.50
Preservative: 0.1% Sodium azide
Constituents: Tissue culture supernatant, Tris buffered saline, 1% BSA -
Concentration information loading... -
Purity
Tissue culture supernatant -
Primary antibody notes
This antibody recognises a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of large cell lymphomas. This rabbit polyclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein. -
Clonality
Monoclonal -
Clone number
SP8 -
Isotype
IgG -
Research areas
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALK antibody [SP8] (ab16670)
Immunohistochemical analysis of Human anaplastic lymphoma tissue labelling ALK with ab16670.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALK antibody [SP8] (ab16670)](https://www.abcam.com/ps/products/16/ab16670/Images/ab16670-209526-anti-alk-antibody-sp8-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALK antibody [SP8] (ab16670)Immunohistochemical analysis of paraffin-embedded Human anaplastic lymphoma tissue labelling ALK with ab16670 at 1/100.
