Amlodipine, L-type calcium channel blocker (ab141900)
Key features and details
- Potent, long-acting L-type calcium channel blocker
- CAS Number: 88150-42-9
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Amlodipine, L-type calcium channel blocker -
Description
Potent, long-acting L-type calcium channel blocker -
Biological description
Potent, long-acting L-type calcium channel blocker (IC50=1.9 nM). Also stimulates nitric oxide synthase (NOS), lowers blood pressure and has antioxidant properties. -
Purity
> 98% -
CAS Number
88150-42-9 -
Chemical structure
Properties
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Chemical name
3-O-Ethyl 5-O-methyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate -
Molecular weight
408.88 -
Molecular formula
C20H25ClN2O5 -
PubChem identifier
2162 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN -
Source
Synthetic
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Research areas