Anti-Kv2.2/KCNB2 antibody (ab101068)
Key features and details
- Rabbit polyclonal to Kv2.2/KCNB2
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-Kv2.2/KCNB2 antibody -
Description
Rabbit polyclonal to Kv2.2/KCNB2 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Rat
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Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- This antibody gave a positive signal in the following tissue lysates: Rat Hippocampus; Rat Whole Brain; Mouse Whole Brain.
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General notes
This product was previously labelled as Kv2.2
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab101068 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB RatAll applications HumanApplication Abreviews Notes WB Use a concentration of 1 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).Notes WB
Use a concentration of 1 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).Target
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Function
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. -
Sequence similarities
Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily. -
Domain
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. -
Post-translational
modificationsPhosphorylated. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 9312 Human
- Entrez Gene: 98741 Mouse
- Entrez Gene: 117105 Rat
- Omim: 607738 Human
- SwissProt: Q92953 Human
- SwissProt: A6H8H5 Mouse
- SwissProt: Q63099 Rat
- Unigene: 661102 Human
see all -
Alternative names
- delayed rectifier potassium channel protein antibody
- KCNB2 antibody
- KCNB2_HUMAN antibody
see all
Images
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Western blot - Anti-Kv2.2/KCNB2 antibody (ab101068)All lanes : Anti-Kv2.2/KCNB2 antibody (ab101068) at 1 µg/ml
Lane 1 : Rat Hippocampus Tissue Lysate
Lane 2 : Brain (Rat) Tissue Lysate
Lane 3 : Brain (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 102 kDa
Observed band size: 102 kDa
Exposure time: 20 minutes
Datasheets and documents
References (0)
ab101068 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-Kv2.2/KCNB2 antibody (ab101068)All lanes : Anti-Kv2.2/KCNB2 antibody (ab101068) at 1 µg/ml
Lane 1 : Rat Hippocampus Tissue Lysate
Lane 2 : Brain (Rat) Tissue Lysate
Lane 3 : Brain (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 102 kDa
Observed band size: 102 kDa
Exposure time: 20 minutes